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sk mel 3  (ATCC)


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    Structured Review

    ATCC sk mel 3
    Sk Mel 3, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 150 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sk+mel/SK-MEL-3/pm42235302-221-2-19
    Average 95 stars, based on 150 article reviews
    sk mel 3 - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Multiple Displacement Amplification:

    Article Title: Oxynitidine derivatives useful as inhibitors of topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1)
    Article Snippet: .. TABLE 3 Cytotoxicity of 19a against NCI-60 cell lines Panel Cell line GI50 (μM)a MGMb 0.145 Leukemia CCRF-CEM 0.144 K-562 0.156 MOLT-4 0.118 RPMI-8226 0.14 SR 0.0669 Non-Small A549/ATCC 0.244 Cell Lung EKVX 0.79 Cancer HOP-62 0.18 HOP-92 0.558 NCI-H226 0.512 NCI-H23 0.201 NCI-H322M 0.428 NCI-H460 0.141 NCI-H522 0.076 Colon COLO 205 0.144 Cancer HCC-2998 0.63 HCT116 0.0855 HCT-15 0.427 HT29 0.149 KM12 0.875 SW-620 0.345 Renal 786-0 0.166 Cancer A498 0.347 ACHN 0.16 CAKI-1 0.186 RXF 393 0.516 SN 12C 0.258 TK-10 0.722 UO-31 0.157 CNS Cancer SF-268 0.283 SF-295 0.177 SF-539 0.186 SNB-19 0.233 SNB-75 0.239 U251 0.14 Melanoma LOX IMVI 0.112 MALME-3M 0.284 M14 0.149 MDA-MB-435 0.395 SK-MEL-2 0.886 SK-MEL-28 0.861 SK-MEL-5 0.181 UACC-257 0.528 UACC-62 0.0966 Breast MCF7 0.118 Cancer MDA-MB- 0.826 231/ATCC HS 578T 1.86 BT-549 0.291 T-47D 0.111 MDA-MB-468 0.14 Ovarian IGROV1 0.312 Cancer OVCAR-3 0.582 OVCAR-4 0.557 OVCAR-5 0.595 OVCAR-8 0.554 NCI/ADR-RES 0.29 SK-OV-3 0.24 Prostate PC-3 0.317 Cancer DU-145 0.215 Regarding Table 3: aGI50 values were defined as the concentrations of compounds that resulted in 50% cell growth inhibition. .. Although the benzophenanthridines 39a/b and 41a/b did not show Top1 inhibition at up to 100 M concentration, they had good Tdp1 inhibitory activity with IC50 values at low micromolar concentration, and showed good cytotoxicity against four cancer cell lines, including CCRF-CEM, DU145, A549 and Huh7 cells, with GI50 values between 1.29 and 8.95 μM, suggesting additional cellular targets.

    Inhibition:

    Article Title: Oxynitidine derivatives useful as inhibitors of topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1)
    Article Snippet: .. TABLE 3 Cytotoxicity of 19a against NCI-60 cell lines Panel Cell line GI50 (μM)a MGMb 0.145 Leukemia CCRF-CEM 0.144 K-562 0.156 MOLT-4 0.118 RPMI-8226 0.14 SR 0.0669 Non-Small A549/ATCC 0.244 Cell Lung EKVX 0.79 Cancer HOP-62 0.18 HOP-92 0.558 NCI-H226 0.512 NCI-H23 0.201 NCI-H322M 0.428 NCI-H460 0.141 NCI-H522 0.076 Colon COLO 205 0.144 Cancer HCC-2998 0.63 HCT116 0.0855 HCT-15 0.427 HT29 0.149 KM12 0.875 SW-620 0.345 Renal 786-0 0.166 Cancer A498 0.347 ACHN 0.16 CAKI-1 0.186 RXF 393 0.516 SN 12C 0.258 TK-10 0.722 UO-31 0.157 CNS Cancer SF-268 0.283 SF-295 0.177 SF-539 0.186 SNB-19 0.233 SNB-75 0.239 U251 0.14 Melanoma LOX IMVI 0.112 MALME-3M 0.284 M14 0.149 MDA-MB-435 0.395 SK-MEL-2 0.886 SK-MEL-28 0.861 SK-MEL-5 0.181 UACC-257 0.528 UACC-62 0.0966 Breast MCF7 0.118 Cancer MDA-MB- 0.826 231/ATCC HS 578T 1.86 BT-549 0.291 T-47D 0.111 MDA-MB-468 0.14 Ovarian IGROV1 0.312 Cancer OVCAR-3 0.582 OVCAR-4 0.557 OVCAR-5 0.595 OVCAR-8 0.554 NCI/ADR-RES 0.29 SK-OV-3 0.24 Prostate PC-3 0.317 Cancer DU-145 0.215 Regarding Table 3: aGI50 values were defined as the concentrations of compounds that resulted in 50% cell growth inhibition. .. Although the benzophenanthridines 39a/b and 41a/b did not show Top1 inhibition at up to 100 M concentration, they had good Tdp1 inhibitory activity with IC50 values at low micromolar concentration, and showed good cytotoxicity against four cancer cell lines, including CCRF-CEM, DU145, A549 and Huh7 cells, with GI50 values between 1.29 and 8.95 μM, suggesting additional cellular targets.

    Cell Culture:

    Article Title: Methods for treating mitochondrial disorders
    Article Snippet: .. SK-MEL-31 human skin cells and A204 human muscle cells were obtained from ATCC®, cultured and maintained in MoCoy-5A medium with 10% FBS, as well as 1% Penicillin and Streptomycin. .. PANC-1 human pancreatic cancer cells were obtained from ATCC®, cultured and maintained in DMEM Medium with 10% FBS as well as 1% Penicillin and Streptomycin.

    Control:

    Article Title: CircANKRD52 Augments the Growth and Invasion of Melanoma Cells by Sponging miR-141-3p and Upregulating PRKACB.
    Article Snippet: .. Human malignant melanoma cell lines A375, Hs294T, SK- MEL- 28 were procured from American Type Culture Collection (ATCC, Manassas, VA, USA) and melanocytes were used as the control cells. .. The cells were cultured in Dulbecco's modified Eagle's medium (DMEM) with 10% foetal bovine serum (Gibco Company, Grand Island, NY, USA) at 37°C with 5% CO2 and 95% humidity.



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